Professional Resources
2008 Professional Meetings
| DATES | CONGRESS | CITY |
| January 16-19 | Advances Against Aspergillosis (AAA) | Miami, FL |
| February 13-17 | American Society for Blood and Marrow Transplantation/Center for International Blood and Marrow Transplant Research (ASBMT/CIBMTR) | San Diego, CA |
| March 5-7 | Focus on Fungal Infections (FOFI) | San Antonio, TX |
| March 5-9 | National Comprehensive Cancer Network (NCCN) | Hollywood, FL |
| March 30-April 2 | European Group for Blood and Marrow Transplantation (EBMT) | Florence, Italy |
| April 19-22 | European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) | Barcelona, Spain |
| May 30-June 3 | American Society of Clinical Oncology (ASCO) | Chicago, IL |
| May 31-June 4 | American Transplant Congress (ATC) | Toronto, Ontario |
| June 22-25 | International Immunocompromised Host Society (ICHS) | Thessaloniki, Greece |
| October 25-28 | Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America (ICAAC/IDSA) | Washington, DC |
| December 6-9 | American Society of Hematology (ASH) | San Francisco, CA |
| December 7-11 | American Society of Health-System Pharmacists (ASHP) | Orlando, FL |
2009 Professional Meetings
| DATES | CONGRESS | CITY |
| February 11-15 | BMT Tandem Meetings (ASBMT/CIBMTR) | Tampa, FL |
| March 11-15 | National Comprehensive Cancer Network (NCCN) | Hollywood, FL |
| March 29-April 1 | European Group for Blood and Marrow Transplantation (EBMT) | Gothenburg, Sweden |
| May 16-19 | European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) | Helsinki, Finland |
| May 25-29 | International Society for Human and Animal Mycology (ISHAM) | Tokyo, Japan |
| May 29-June 2 | American Society of Clinical Oncology (ASCO) | Orlando, FL |
| May 30-June 3 | American Transplant Congress (ATC) | Boston, MA |
| September 12-15 | Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) | San Francisco, CA |
| October 18-21 | Trends in Medical Mycology (TIMM) | Athens, Greece |
| October 29-November 1 | Infectious Diseases Society of America (IDSA) | Philadelphia, PA |
| December 5-8 | American Society of Hematology (ASH) | New Orleans, LA |
| December 6-10 | American Society of Health-System Pharmacists (ASHP) | Las Vegas, NV |
Professional Meetings:
American Society for Blood and Marrow Transplantation
ASBMT is a national professional association that promotes advancement of the field of cellular therapy and blood and bone marrow transplantation. Members of ASBMT are in both clinical practice and research, involved in a broad range of activities including patient care and interaction with government, private agencies, and industry.
American Society for Microbiology
ASM is the oldest and largest single life science membership organization in the world. The members represent 26 disciplines of microbiological specialization plus a division for microbiology educators. The mission of ASM is to advance microbiological sciences through the pursuit of scientific knowledge and dissemination of the results of fundamental and applied research. ICAAC is one of the annual meetings sponsored by ASM.
American Society of Clinical Oncology
ASCO is a non-profit organization, committed to advancing the education of oncologists and other oncology professionals, advocating for policies that provide access to high-quality cancer care, and supporting the clinical trials system and the need for increased clinical and translational research. ASCO is the world’s leading professional organization representing physicians who treat people with cancer.
American Society of Health-System Pharmacists
ASHP is the 30,000-member national professional association that represents pharmacists who practice in hospitals, health maintenance organizations, long-term care facilities, home care, and other components of health care systems. The mission of ASHP is to assist pharmacists in helping people make the best use of medicines.
American Society of Hematology
ASH has played an active and important role in the development of hematology as a discipline. By promoting research, clinical care, education, training, and advocacy in hematology, the society aims to further the understanding, diagnosis, treatment, and prevention of disorders affecting the blood, the bone marrow, and the immunologic, hemostatic, and vascular systems.
American Society of Transplantation
AST is an international organization of transplant professionals dedicated to advancing the field of transplantation through the promotion of research, education, advocacy, and organ donation to improve patient care. The goal of AST is to offer a forum for the exchange of knowledge, scientific information, and expertise in the field of transplantation. ATC is one of the annual meetings hosted by AST.
American Society of Transplant Surgeons
ASTS is a non-profit organization which has established a strong presence in transplantation research, education and training, and advocacy. The members represent transplant surgeons, physicians, scientists, and allied health professionals from all around the globe. The mission of ASTS is to foster and advance the practice and science of transplantation for the benefit of patients and society; to guide those who make policy decisions that influence the practice and science of transplantation; defining and promoting training and career-long education of its members; and advancing the professional development and careers of its members. ATC is one of the annual meetings hosted by ASTS.
Center for International Blood and Marrow Transplant Research
CIBMTR brings together the expertise and unique resources of two leaders in the field of blood and marrow transplant research: the National Marrow Donor Program® and the Medical College of Wisconsin's International Bone Marrow Transplant Registry and Autologous Blood and Marrow Transplant Registry. CIBMTR’s goal is to help more transplant patients live longer, healthier lives by designing, conducting, and supporting clinical studies that involve large numbers of patients from multiple transplant centers.
European Group for Blood and Marrow Transplantation
EBMT is a non-profit organisation based in Maastricht, The Netherlands, that was established in 1974 in order to allow scientists and physicians involved in clinical bone marrow transplantation to share their experience and develop co-operative studies. The EBMT aims to promote all aspects associated with the transplantation of haematopoietic stem cells from all donor sources and donor types including basic and clinical research, education, standardisation, quality control, and accreditation for transplant procedures.
European Society for Clinical Microbiology and Infectious Diseases
ESCMID is a non-profit organisation whose mission is to improve the diagnosis, treatment and prevention of infectious diseases by promoting and supporting research, education and training in the infection disciplines. This is achieved by scientific exchange, educational programmes, grants and awards, certification and consultation with professional and government agencies. Through its activities and publications ESCMID fosters professional exchange and stimulates an open and collaborative spirit nourished by the diversity of European culture.
Infectious Diseases Society of America
IDSA members include physicians, scientists, and other health care professionals who specialize in infectious diseases. IDSA’s purpose is to improve the health of individuals, communities, and society by promoting excellence in patient care, education, research, public health, and prevention relating to infectious diseases.
International Immunocompromised Host Society
The ICHS is the premier, international, multi-disciplinary forum for scientific and clinical interchange to improve understanding and management of the immunocompromised host.
International Society for Human and Animal Mycology
ISHAM is a world wide organization that represents all clinical scientists and fundamental researchers with interest in fungal diseases. ISHAM is an independent society that is non-political and non-discriminatory. It exists solely to encourage and facilitate the study and practice of all aspects of medical and veterinary mycology.
National Comprehensive Cancer Network
NCCN is a not-for-profit alliance of 21 of the world’s leading cancer centers. The group promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers. The primary goal of NCCN is to improve the quality, effectiveness, and efficiency of oncology practice so patients can live better lives.
Trends in Medical Mycology
TIMM-4 is the fourth in the series of TIMM mycological international meetings organized jointly by the European Confederation of Medical Mycology (ECMM) and by the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer (IDG-EORTC). TIMM has become an important meeting in the field of fungal infections: a forum in which investigators and clinicians from all over the world exchange research results and opinions on medical practice. Well-known speakers discuss the most important advances in basic science and clinical research in mycology.
National Marrow Donor Program is a registered trademark of the National Marrow Donor Program.
Important Safety Information
NOXAFIL® has been shown to interact with several medications, including drugs that suppress the immune system, and these reactions may be serious. The product label should be consulted when other drugs are prescribed with NOXAFIL®.
Coadministration with sirolimus or ergot alkaloids is contraindicated. Coadministration with the CYP3A4 substrates terfenadine, astemizole, cisapride, pimozide, halofantrine, or quinidine, is also contraindicated since this may result in increased plasma concentrations of these medicinal products, leading to QTc prolongation and rare occurrences of torsades de pointes.
Serious and rare fatal toxicity from cyclosporine has occurred when taken in combination with NOXAFIL® and therefore reduction of the dose of drugs like cyclosporine or tacrolimus and frequent monitoring of drug levels of these medications are necessary when taking them in combination with NOXAFIL®.
In clinical trials, there were infrequent cases of hepatic reactions (eg, mild to moderate elevations in ALT, AST, alkaline phosphatase, total bilirubin, and/or clinical hepatitis). Rarely, more severe hepatic reactions including cholestasis or hepatic failure including fatalities were reported in patients with serious underlying medical conditions (eg, hematologic malignancies) during treatment with posaconazole. Liver function tests should be monitored at the start of and during the course of therapy. Discontinuation of NOXAFIL® must be considered in patients who experience symptoms consistent with liver disease that may be attributable to NOXAFIL®.
The safety and effectiveness of NOXAFIL® in patients below the age of 13 years old have not been established.
The most common treatment-related serious adverse events (1% each) in the combined prophylaxis studies were bilirubinemia, increased hepatic enzymes, hepatocellular damage, nausea, and vomiting.
In the pooled prophylaxis safety analysis, fever, headache, anemia, diarrhea, nausea, vomiting, abdominal pain, hypokalemia, and thrombocytopenia were frequently reported treatment-emergent adverse events.
In clinical studies of OPC and refractory OPC, adverse events were reported more frequently in the pool of patients with refractory OPC. The most commonly reported serious adverse events in refractory OPC patients included fever (13%) and neutropenia (10%).
